Hopkins Marine Station Student Paper

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(full paper is archived in the Miller Library)

Title: Transmission between stellar nerves and circular muscle of the squid Loliligo opalescens
Student Author(s): Kernie, Steven G.
Faculty Advisor(s): Gilly, W. F.
Pages: 26
Location: Final Papers Biology 175H
Date: June 1987
Keywords: biology of cephalopods
Abstract: Neuromuscular transmission in the squid is described in terms of the slow and fast fibers characterizing circular mantle muscle. Various potential transmitter substances and antagonists to synaptic transmission were tested by electrically stimulating giant fibers and recording twitch responses of the circular muscle in the presence of the substances tested. Of these, bath application of L-glutamate had an excitatory effect on circular mantle tissue. Antagonists to L-glutamate known to mediate synaptic transmission in other neuromuscular systems had no reversible inhibitory effect on transmission. It is concluded that L-glutamate or a glutamate analog may directly excite the slow circular fiber. The apparently inhibiting action of glutamate on fast fibers innervated by the giatn axons may arise either presynaptically or postsynaptically.