(full paper is archived in the Miller Library)
Title: The egg peptide Speract increases fertilization of the sea urchin S. purpuratus
Student Author(s): Sansoni, Stephanie Bridget
Faculty Advisor(s): Epel, David
Location: Final Papers Biology 175H
Date: June 1990
Abstract: It was demonstrated that the addition of 10nM speract to gametes of Strongylocentrotus purpuratus dramatically increases fertilization in standard laboratory conditions and under the effect of turbulence. Such an increase in fertiliztion has not been observed by other researchers; the difference in results is likely due to bariations in experimental conditions, in particular egg suspension (personal communications from D. Garbers, N. Suzuki, and V.D. Vacquier). Speract's mechanism of action remains unresolved; this paper suggests that there is a low-affinity receptor on the sperm tail to which speract binds, possibly causing changes in sperm metabolism.